Advanced Light Source, 1 Cyclotron Road, Berkeley, CA 94720


Mesocale Cell imaging


Sontag, E. M., Morales-Polanco, F., Chen, J.-H., McDermott, G., Dolan, P.T., Gestaut, D., Le Gros, M.A., Larabell, C., & Frydman, J. (2023) Nuclear and cytoplasmic spatial protein quality control is coordinated by nuclear–vacuolar junctions and perinuclear ESCRT. Nat. Cell Biol. doi:10.1038/s41556-023-01128-6

Eng, T., Banerjee, D., Menasalvas, J., Chen, Y., Gin, j., Choudhary, H., Baidoo, E., Chen, J.-H., Ekman, A., Kakumanu, R., Diercks, Y.L., Codik, A., Larabell, C., Gladden, J., Simmons, B., Keasling, J.D., Petzold, C.J., & Mukhopadhyay, A. (2023) Ensemble and Iterative Engineering for Maximized Bioconversion to the Blue Pigment, Indigoidine from Non-Canonical Sustainable Carbon Sources. bioRxiv 2023.03.16.532821; doi:10.1101/2023.03.16.532821

Boeynaems, S., Ma, X.R., Yeong, V., Ginell, G.M., Chen, J.-H., Blum, J.A., Nakayama, L., Sanyal, A., Briner, A., Van Haver, D., Pauwels, J., Ekman, A., Schmidt, H. B., Sundararajan, K., Porta, L., Lasker, K., Larabell, C., Hayashi, M.A.F., Kundaje, A., Impens, F., Obermeyer, A., Holehouse, A.S., & Gitler, A.D. (2023) Aberrant phase separation is a common killing strategy of positively charged peptides in biology and human disease. bioRxiv 2023.03.09.531820; doi:10.1101/2023.03.09.531820

Ekman, A., Chen, J.-H., Vanslembrouck, B., Loconte, V., Larabell, C., Le Gros, M., & Weinhardt, V. (2023) Extending of imaging volume in soft x-ray tomographyAdv. Photonics Res. 2200142. doi:10.1002/adpr.202200142

Loconte, V., Chen, J.-H., Vanslembrouck, B., Ekman, A.A. McDermott, G., Le Gros, M.A., & Larabell, C.A. (2023) Soft X-ray tomograms provide a structural basis for whole-cell modeling. The FASEB Journal, 37:e22681. doi:10.1096/fj.202200253R


Chen, J.-H., Vanslembrouck, B., Ekman, A., Aho, V., Larabell, C.A., Le Gros, M.A., Vihinen-Ranta, M., & Weinhardt, V. (2022) Soft X-ray Tomography Reveals HSV-1-Induced Remodeling of Human B Cells. Viruses 14, 2651. doi:10.3390/v14122651

Li, A., Zhang, S., Loconte, V., Liu, Y., Ekman, A., Thompson, G.J., Sali, A., Stevens, C.R., White, K., Singla, J., & Sun, L. (2022) An intensity-based post-processing tool for 3D instance segmentation of organelles in soft X-ray tomograms. PLoS ONE 17(9): e0269887. doi:10.1371/journal.pone.0269887

Autin, L., Barbaro, B., Jewett, A., Ekman, A., Verma, S., Olson, A., & Goodsell, D. (2022). Integrative structural modelling and visualisation of a cellular organelle. QRB Discovery, 3, E11. doi:10.1017/qrd.2022.10

Hueschen, C.L., Zarko L.S., Chen, J.H., LeGros, M.A., Larabell, C.A., Boothroyd, J.C., Phillips, & R., Dunn, A.R. (2022). Emergent Actin Flows Explain Diverse Parasite Gliding Modes. bioRxiv, 495399; doi: 10.1101/2022.06.08.49539

Vanslembrouck, B., Chen, J.-H., Larabell, C., & van Hengel, J. (2022). Microscopic Visualization of Cell-Cell Adhesion Complexes at Micro and Nanoscale. Front. Cell Dev. Biol., 10:819534. doi:10.3389/fcell.2022.819534

Li, A., Zhang, X., Singla, J., White, K.L., Loconte, V., Hu, C., Zhang, C., Li, S., Li, W., Francis, J.P., Wang, C., Sali, A., Sun, L., He, X., & Stevens, R. (2022). Auto-segmentation and time-dependent systematic analysis of mesoscale cellular structure in β-cells during insulin secretion. PLoS ONE, 17(3), e0265567. doi:10.1371/journal.pone.0265567

Loconte, V., Singla, J., Li, A., Chen, J.-H., Ekman, A., McDermott, G., Sali, A., Le Gros, M., White, K.L., & Larabell, C. A. (2022). Soft X-ray tomography to map and quantify organelle interactions at the mesoscale. Structure, 30, 1-12. doi:10.1016/j.str.2022.01.006

Chen, J.-H., Vanslembrouck, B., Loconte, V., Ekman, A., Cortese, M., Bartenschlager, R., McDermott, G., Larabell, C.A., Le Gros, M.A., & Weinhardt, V. (2022). A protocol for full-rotation soft X-ray tomography of single cells. STAR Protocols, 3(1), 101176. doi:10.1016/j.xpro.2022.101176


Loconte, V., & White, K. L. (2021). The use of soft X-ray tomography to explore mitochondrial structure and function. Molecular Metabolism, 101421. doi:10.1016/j.molmet.2021.101421

Loconte, V., Chen, J.H., Cortese, M., Ekman, A., Le Gros, M.A., Larabell, C.A., Bartenschlager, R., & Weinhardt, V. (2021). Using soft X-ray tomography for rapid whole-cell quantitative imaging of SARS-CoV-2-infected cells. Cell Reports Methods, 1(7), 100117. doi:10.1016/j.crmeth.2021.100117

Raveh, B., Sun, L., White, K. L., Sanyal, T., Tempkin, J., Zheng, D., Bharat, K., Singla, J., Wang, C.X., Zhao, J., Li, A., Graham, N.A., Kesselman, C., Stevens, R.C., & Sali, A. (2021). Bayesian metamodeling of complex biological systems across varying representations. Proceedings of the National Academy of Sciences, 118(35), e2104559118. doi:10.1073/pnas.2104559118

Levine, Z. H., Garboczi, E. J., Peskin, A. P., Ekman, A. A., Mansfield, E., & Holm, J. D. (2021). X-ray computed tomography using partially coherent Fresnel diffraction with application to an optical fiber. Optics Express, 29(2), 1788-1804. doi:10.1364/OE.414398


White, K. L., Singla, J., Loconte, V., Chen, J. H., Ekman, A., Sun, L., Zhang, X., Francis, J.P., Li, A., Lin, W., Tseng, K., McDermott, G., Alber, F., Sali, A., Larabell, C., & Stevens, R. C. (2020). Visualizing subcellular rearrangements in intact β cells using soft x-ray tomography. Science Advances, 6(50), 1-13. doi:10.1126/sciadv.abc8262

Polo, C. C., Fonseca-Alaniz, M. H., Chen, J. H., Ekman, A., McDermott, G., Meneau, F., Krieger, J.E., & Miyakawa, A. A. (2020). Three-dimensional imaging of mitochondrial cristae complexity using cryo-soft X-ray tomography. Scientific Reports, 10(1), 1-8. doi:10.1038/s41598-020-78150-3

Weinhardt, V., Chen, J. H., Ekman, A. A., Guo, J., Remesh, S. G., Hammel, M., McDermott, G., Chao, W., Oh, S., Le Gros, M.A., & Larabell, C. A. (2020). Switchable resolution in soft x-ray tomography of single cells. PLoS ONE, 15(1), 1-14. doi:10.1371/journal.pone.0227601

Remesh, S. G., Verma, S. C., Chen, J. H., Ekman, A. A., Larabell, C. A., Adhya, S., & Hammel, M. (2020). Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling. Nature Communications, 11(1), 1-12. doi:10.1038/s41467-020-16724-5

Ma, J., Do, M., Le Gros, M. A., Peskin, C. S., Larabell, C. A., Mori, Y., & Isaacson, S. A. (2020). Strong intracellular signal inactivation produces sharper and more robust signaling from cell membrane to nucleus. PLoS Computational Biology, 16(11), 1-19. doi:10.1371/journal.pcbi.1008356


Guo, J., & Larabell, C. A. (2019). Soft X-ray tomography: virtual sculptures from cell cultures. Current Opinion in Structural Biology, 58, 324-332. doi:10.1016/

Weinhardt, V., Chen, J. H., Ekman, A., McDermott, G., Le Gros, M. A., & Larabell, C. (2019). Imaging cell morphology and physiology using X-rays. Biochemical Society Transactions, 47, 489-508. doi:10.1042/BST20180036

Walters, A. D., Amoateng, K., Wang, R., Chen, J.-H., McDermott, G., Larabell, C. A., Gadal, O., & Cohen-Fix, O. (2018). Nuclear envelope expansion in budding yeast is independent of cell growth and does not determine nuclear volume. Molecular Biology of the Cell, 30(1), 131-145. doi:10.1091/mbc.E18-04-0204

Roth, M. S., Gallaher, S. D., Westcott, D. J., Iwai, M., Louie, K. B., Mueller, M., Walter, A., Foflonker, F., Bowen, B.P., Ataii, N.N., Song, J., Chen, J.H., Blaby-Haas, C.E., Larabell, C., Auer, M., Northen, T.R., Merchant, S.S., & Niyogi, K. K. (2019). Regulation of oxygenic photosynthesis during trophic transitions in the green alga Chromochloris Zofingiensis. Plant Cell, 31(3), 579-601. doi:10.1105/tpc.18.00742

Boeynaems, S., Holehouse, A. S., Weinhardt, V., Kovacs, D., Van Lindt, J., Larabell, C., Van Den Bosch, L., Das, R., Tompa, P.S., Pappu, R.V., & Gitler, A. D. (2019). Spontaneous driving forces give rise to protein−RNA condensates with coexisting phases and complex material properties. Proceedings of the National Academy of Sciences, 116(16), 7889. doi:10.1073/pnas.1821038116

Aho, V., Mäntylä, E., Ekman, A., Hakanen, S., Mattola, S., Chen, J.-H., Weinhardt, V., Ruokolainen, V., Sodeik, B., Larabell, C., & Vihinen-Ranta, M. (2019). Quantitative Microscopy Reveals Stepwise Alteration of Chromatin Structure during Herpesvirus Infection. Viruses, 11(10). doi:10.3390/v11100935


Smallwood, C. R., Chrisler, W., Chen, J.-H., Patello, E., Thomas, M., Boudreau, R., Ekman, A., Wang, H., McDermott, G., & Evans, J. E. (2018). Ostreococcus tauri is a high-lipid content green algae that extrudes clustered lipid droplets. bioRxiv, 249052. doi:10.1101/249052

Smallwood, C. R., Chen, J.-H., Kumar, N., Chrisler, W., Purvine, S. O., Kyle, J. E., Nicora, C.D., Boudreau, R., Ekman, A., Hixson, K.K., Moore, R.J., McDermott, G., Cannon, W.R., & Evans, J. E. (2018). Integrated systems biology and imaging of the smallest free-living eukaryote Ostreococcus tauri. bioRxiv, 293704. doi:10.1101/293704

Pelt, D. M., & Sethian, J. A. (2018). A mixed-scale dense convolutional neural network for image analysis. Proceedings of the National Academy of Sciences, 115(2), 254. doi:10.1073/pnas.1715832114

Mehta, A. P., Supekova, L., Chen, J.-H., Pestonjamasp, K., Webster, P., Ko, Y., Henderson, S.C., McDermott, G., Supek, F., & Schultz, P. G. (2018). Engineering yeast endosymbionts as a step toward the evolution of mitochondria. Proceedings of the National Academy of Sciences, 115(46), 11796. doi:10.1073/pnas.1813143115

Ekman, A., Weinhardt, V., Chen, J. H., McDermott, G., Le Gros, M. A., & Larabell, C. (2018). PSF correction in soft X-ray tomography. Journal of Structural Biology, 204(1), 9-18. doi:10.1016/j.jsb.2018.06.003


Dekker, J., Belmont, A. S., Guttman, M., Leshyk, V. O., Lis, J. T., Lomvardas, S., Mirny, L.A., O’Shea, C.C., Park, P.J., Ren, B., Ritland Politz, J.C., Shendure, J., Zhong, S., & the 4D Nucleome Network. (2017). The 4D nucleome project. Nature, 549(7671), 219-226. doi:10.1038/nature23884

Roth, M. S., Cokus, S. J., Gallaher, S. D., Walter, A., Lopez, D., Erickson, E., Endelman, B., Westcott, D., Larabell, C.A., Merchant, S.S., Pellegrini, M., & Niyogi, K. K. (2017). Chromosome-level genome assembly and transcriptome of the green alga Chromochloris zofingiensis illuminates astaxanthin production. Proceedings of the National Academy of Sciences, 114(21), E4296. doi:10.1073/pnas.1619928114

Chongsiriwatana, N. P., Lin, J. S., Kapoor, R., Wetzler, M., Rea, J. A. C., Didwania, M. K., Contag, C.H., & Barron, A. E. (2017). Intracellular biomass flocculation as a key mechanism of rapid bacterial killing by cationic, amphipathic antimicrobial peptides and peptoids. Scientific Reports, 7(1), 16718. doi:10.1038/s41598-017-16180-0

Ekman, A. A., Chen, J. H., Guo, J., McDermott, G., Le Gros, M. A., & Larabell, C. A. (2017). Mesoscale imaging with cryo-light and X-rays: Larger than molecular machines, smaller than a cell. Biology of the Cell, 109(1), 24-38. doi:10.1111/boc.201600044

Aho, V., Myllys, M., Ruokolainen, V., Hakanen, S., Mantyla, E., Virtanen, J., Hukkanen, V., Kuhn, T., Timonen, J., Mattila, K., Larabell, C.A. & Vihinen-Ranta, M. (2017). Chromatin organization regulates viral egress dynamicsScientific Reports, 7, doi:10.1038/s41598-017-03630-y

Seo, A. Y., Lau, P.-W., Feliciano, D., Sengupta, P., Gros, M. A. L., Cinquin, B., Larabell, C.A., & Lippincott-Schwartz, J. (2017). AMPK and vacuole-associated Atg14p orchestrate μ-lipophagy for energy production and long-term survival under glucose starvation. eLife, 6, e21690. doi:10.7554/eLife.21690


LeGros, M. A., Clowney, E. J., Magklara, A., Yen, A., Markenscoff-Papadimitriou, E., Colquitt, B., Myllys, M., Kellis, M., Lomvardas, S., & Larabell, C. A. (2016). Soft x-ray tomography reveals gradual chromatin compaction and reorganization during neurogenesis in vivo. Cell Report, 17(8), 2125-2136. doi:10.1016/j.celrep.2016.10.060

LeGros, M. A., Chen, J.-H., Do, M., McDermott, G., & Larabell, C. A. (2016). Putting Molecules in the Picture: Using Correlated Light Microscopy and Soft X-Ray Tomography to Study Cells. Synchrotron Light Sources and Free-Electron Lasers: Accelerator Physics, Instrumentation and Science Applications, 1367-1391. doi:10.1007/978-3-319-14394-1_43

Tjong, H., Li, W., Kalhor, R., Dai, C., Hao, S., Gong, K., Zhou, Y., Li, H., Zhou, X.J., Le Gros, M.A., Larabell, C.A., Chen, L., & Alber, F. (2016). Population-based 3D genome structure analysis reveals driving forces in spatial genome organization. Proceedings of the National Academy of Sciences, 113(12), E1663-E1672. doi:10.1073/pnas.1512577113

Myllys, M., Ruokolainen, V., Aho, V., Smith, E. A., Hakanen, S., Peri, P., Salvetti, A., Timonen, J., Hukkanen, V., Larabell, C.A., & Vihinen-Ranta, M. (2016). Herpes simplex virus 1 induces egress channels through marginalized host chromatin. Scientific Reports, 6(1), 28844. doi:10.1038/srep28844

Hammel, M., Amlanjyoti, D., Reyes, F. E., Chen, J. H., Parpana, R., Tang, H. Y., Larabell, C.A., Tainer, J.A., & Adhya, S. (2016). HU multimerization shift controls nucleoid compaction. Science Advances, 2(7), e1600650. doi:10.1126/sciadv.1600650

Darrow, M. C., Zhang, Y. J., Cinquin, B. P., Smith, E. A., Boudreau, R., Rochat, R. H., Schmid, M.F., Xia, Y., Larabell, C.A., & Chiu, W. (2016). Visualizing red blood cell sickling and the effects of inhibition of sphingosine kinase 1 using soft X-ray tomography. Journal of Cell Science, 129(18), 3511-3517. doi:10.1242/jcs.189225


Ugarte, F., Sousae, R., Cinquin, B., Martin, E. W., Krietsch, J., Sanchez, G., Inman, M., Tsang, H., Warr, M., Passegue, E., Larabell, C.A., & Forsberg, E. C. (2015). Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells. Stem Cell Reports, 5(5), 728-740. doi:10.1016/j.stemcr.2015.09.009

Elgass, K. D., Smith, E. A., LeGros, M. A., Larabell, C. A., & Ryan, M. T. (2015). Analysis of ER-mitochondria contacts using correlative fluorescence microscopy and soft X-ray tomography of mammalian cells. Journal of Cell Science, 128(15), 2795-2804. doi:10.1242/jcs.169136

Do, M., Isaacson, S. A., McDermott, G., Le Gros, M. A., & Larabell, C. A. (2015). Imaging and characterizing cells using tomography. Arch Biochem Biophys, 581, 111-121. doi:10.1016/


Walters, Alison D., May, Christopher K., Dauster, Emma S., Cinquin, Bertrand P., Smith, Elizabeth A., Robellet, X., D’Amours, D., Larabell, C.A., & Cohen-Fix, O. (2014). The Yeast Polo Kinase Cdc5 Regulates the Shape of the Mitotic Nucleus. Current Biology, 24(23), 2861-2867. doi:10.1016/j.cub.2014.10.029

Smith, E. A., McDermott, G., Do, M., Leung, K., Panning, B., Le Gros, M. A., & Larabell, C. A. (2014). Quantitatively imaging chromosomes by correlated cryo-fluorescence and soft x-ray tomographies. Biophysical Journal, 107(8), 1988-1996. doi:10.1016/j.bpj.2014.09.011

Smith, E. A., Cinquin, B. P., Do, M., McDermott, G., Le Gros, M. A., & Larabell, C. A. (2014). Correlative cryogenic tomography of cells using light and soft x-rays. Ultramicroscopy, 143, 33-40. doi:10.1016/j.ultramic.2013.10.013

Le Gros, M. A., McDermott, G., Cinquin, B. P., Smith, E. A., Do, M., Chao, W. L., Naulleau, P.P., & Larabell, C. A. (2014). Biological soft X-ray tomography on beamline 2.1 at the Advanced Light Source. Journal of Synchrotron Radiation, 21(6), 1370-1377. doi:10.1107/S1600577514015033

Cinquin, B. P., Do, M., McDermott, G., Walters, A. D., Myllys, M., Smith, E. A., Cohen-Fix, O., Le Gros, M.A., & Larabell, C. A. (2014). Putting Molecules in Their Place. Journal of Cellular Biochemistry, 115(2), 209-216. doi:10.1002/jcb.24658

Dasgupta, S., Auth, T., Gov, Nir S., Satchwell, Timothy J., Hanssen, E., Zuccala, Elizabeth S., Riglar, D.T., Toye, A.M., Betz, T., Baum, J., & Gompper, G. (2014). Membrane-Wrapping Contributions to Malaria Parasite Invasion of the Human Erythrocyte. Biophysical Journal, 107(1), 43-54. doi:10.1016/j.bpj.2014.05.024

Patwardhan, A., Ashton, A., Brandt, R., Butcher, S., Carzaniga, R., Chiu, W., Collinson, L., Doux, P., Duke, E., Ellisman, MH., Franken, E., Grünewald, K., Heriche, J.K., Koster, A., Kühlbrandt, W., Lagerstedt, I., Larabell, C., Lawson, C.L., Saibil, H.R., Sanz-García, E., Subramaniam, S., Verkade, P., Swedlow, J.R., & Kleywegt, G. J. (2014). A 3D cellular context for the macromolecular world. Nat Struct Mol Biol, 21(10), 841-845. doi:10.1038/nsmb.2897


Smith, E. A., Cinquin, B. P., McDermott, G., Le Gros, M. A., Parkinson, D. Y., Kim, H. T., & Larabell, C. A. (2013). Correlative microscopy methods that maximize specimen fidelity and data completeness, and improve molecular localization capabilities. Journal of Structural Biology, 184(1), 12-20. doi:10.1016/j.jsb.2013.03.006

Parkinson, D. Y., Epperly, L. R., McDermott, G., Le Gros, M. A., Boudreau, R. M., & Larabell, C. A. (2013). Nanoimaging cells using soft X-ray tomography. Methods Mol Biol, 950, 457-481. doi:10.1007/978-1-62703-137-0_25

Isaacson, S. A., Larabell, C. A., Le Gros, M. A., McQueen, D. M., & Peskin, C. S. (2013). The influence of spatial variation in chromatin density determined by X-ray tomograms on the time to find DNA binding sites. Bull Math Biol, 75(11), 2093-2117. doi:10.1007/s11538-013-9883-9

Hanssen, E., Dekiwadia, C., Riglar, D. T., Rug, M., Lemgruber, L., Cowman, A. F., Cyrklaff, M., Kudryashev, M., Frischknecht, F., Baum, J., & Ralph, S. A. (2013). Electron tomography of Plasmodium falciparum merozoites reveals core cellular events that underpin erythrocyte invasion. Cellular Microbiology, 15(9), 1457-1472. doi:10.1111/cmi.12132

Le Gros, M. A., Knoechel, C. G., Uchida, M., Parkinson, D. Y., McDermott, G., & Larabell, C. A. (2012). Visualizing Sub-cellular Organization Using Soft X-ray Tomography. In E. H. Egelman (Ed.), Comprehensive Biophysics (pp. 90 – 110). Amsterdam: Elsevier


Clowney, E. J., LeGros, Mark A., Mosley, Colleen P., Clowney, Fiona G., Markenskoff-Papadimitriou, Eirene C., Myllys, M., Barnea, G., Larabell, C., & Lomvardas, S. (2012). Nuclear Aggregation of Olfactory Receptor Genes Governs Their Monogenic Expression. Cell, 151(4), 724-737. doi:10.1016/j.cell.2012.09.043

Parkinson, D. Y., Knoechel, C., Yang, C., Larabell, C. A., & Le Gros, M. A. (2012). Automatic alignment and reconstruction of images for soft X-ray tomography. Journal of Structural Biology, 177(2), 259-266. doi:10.1016/j.jsb.2011.11.027

McDermott, G., Le Gros, M. A., & Larabell, C. A. (2012). Visualizing Cell Architecture and Molecular Location Using Soft X-Ray Tomography and Correlated Cryo-Light Microscopy. Annual Review of Physical Chemistry, Vol 63, 63, 225-239. doi:10.1146/annurev-physchem-032511-143818

McDermott, G., Fox, D. M., Epperly, L., Wetzler, M., Barron, A. E., Le Gros, M. A., & Larabell, C. A. (2012). Visualizing and quantifying cell phenotype using soft X-ray tomography. BioEssays, 34(4), 320-327. doi:10.1002/bies.201100125

Hanssen, E., Knoechel, C., Dearnley, M., Dixon, M. W., Le Gros, M., Larabell, C., & Tilley, L. (2012). Soft X-ray microscopy analysis of cell volume and hemoglobin content in erythrocytes infected with asexual and sexual stages of Plasmodium falciparum. Journal of Structural Biology, 177(2), 224-232. doi:10.1016/j.jsb.2011.09.003

Murphy, S. V., Lim, R., Heraud, P., Cholewa, M., Le Gros, M., de Jonge, M. D., Howard, D.L., Paterson, D., McDonald, C., Atala, A., Jenkin, G., & Wallace, E. M. (2012). Human Amnion Epithelial Cells Induced to Express Functional Cystic Fibrosis Transmembrane Conductance Regulator. PLoS ONE, 7(9), e46533. doi:10.1371/journal.pone.0046533


Uchida, M., Sun, Y., McDermott, G., Knoechel, C., Le Gros, M. A., Parkinson, D., Drubin, D.G., & Larabell, C. A. (2011). Quantitative analysis of yeast internal architecture using soft X-ray tomography. Yeast, 28(3), 227-236. doi:10.1002/yea.1834

Hanssen, E., Knoechel, C., Klonis, N., Abu-Bakar, N., Deed, S., LeGros, M., Larabell, C., & Tilley, L. (2011). Cryo transmission X-ray imaging of the malaria parasite, P. falciparum. Journal of Structural Biology, 173(1), 161-168. doi:10.1016/j.jsb.2010.08.013


Larabell, C. A., & Nugent, K. A. (2010). Imaging cellular architecture with X-rays. Curr Opin Struct Biol, 20(5), 623-631. doi:10.1016/


Uchida, M., McDermott, G., Wetzler, M., Le Gros, M. A., Myllys, M., Knoechel, C., Barron, A.E., & Larabell, C. A. (2009). Soft X-ray tomography of phenotypic switching and the cellular response to antifungal peptoids in Candida albicans. Proceedings of the National Academy of Sciences, 106(46), 19375. doi:10.1073/pnas.0906145106

McDermott, G., Le Gros, M. A., Knoechel, C. G., Uchida, M., & Larabell, C. A. (2009). Soft X-ray tomography and cryogenic light microscopy: the cool combination in cellular imaging. Trends in Cell Biology, 19(11), 587-595. doi:10.1016/j.tcb.2009.08.005

Le Gros, M. A., McDermott, G., Uchida, M., Knoechel, C. G., & Larabell, C. A. (2009). High-aperture cryogenic light microscopy. Journal of Microscopy, 235(1), 1-8. doi:10.1111/j.1365-2818.2009.03184.x


Parkinson, D. Y., McDermott, G., Etkin, L. D., Le Gros, M. A., & Larabell, C. A. (2008). Quantitative 3-D imaging of eukaryotic cells using soft X-ray tomography. Journal of Structural Biology, 162(3), 380-386. doi:10.1016/j.jsb.2008.02.003

Ashcroft, J. M., Gu, W., Zhang, T., Hughes, S. M., Hartman, K. B., Hofmann, C., Kanaras, A.G., Kilcoyne, D.A., Le Gros, M., Yin, Y., Alivisatos, A.P., & Larabell, C.A. (2008). TiO2 nanoparticles as a soft X-ray molecular probe. Chemical Communications, 21, 2471-2473. doi:10.1039/b801392f


Tang, Y. J., Ashcroft, J. M., Chen, D., Min, G., Kim, C.-H., Murkhejee, B., Larabell, C., Keasling, J.D., & Chen, F. F. (2007). Charge-Associated Effects of Fullerene Derivatives on Microbial Structural Integrity and Central Metabolism. Nano Letters, 7(3), 754-760. doi:10.1021/nl063020t

Gu, W., Etkin, L. D., Le Gros, M. A., & Larabell, C. A. (2007). X-ray tomography of Schizosaccharomyces pombe. Differentiation, 75(6), 529-535. doi:10.1111/j.1432-0436.2007.00180.x


Attwood, D., Chao, W., Anderson, E. H., Liddle, J. A., Harteneck, B. D., Fisher, P., Schneider, G., Le Gros, M., & Larabell, C. (2006). Imaging at High Spatial Resolution: Soft X-ray Microscopy to 15 nm. Journal of Biomedical Nanotechnology, 2(2), 75-78.  


Fu, A., Gu, W., Larabell, C., & Alivisatos, A. P. (2005). Semiconductor nanocrystals for biological imaging. Current Opinion in Neurobiology, 15(5), 568-575. doi:10.1016/j.conb.2005.08.004


Larabell, C.A., & Le Gros, M.A. (2004). Whole cell cryo X-ray tomography and protein localization at 50 nanometer resolutionBiophysical Journal86, 185A-185A.  

Larabell, C. A., & Le Gros, M. A. (2004). X-ray tomography generates 3-D reconstructions of the yeast, Saccharomyces cerevisiae, at 60-nm resolution. Molecular Biology of the Cell, 15(3), 957-962. doi:10.1091/mbc.E03-07-0522


Weaver, C., Farr, G. H., III, Pan, W., Rowning, B. A., Wang, J., Mao, J., Wu, D., Li, L., Larabell, C.A., & Kimelman, D. (2003). GBP binds kinesin light chain and translocates during cortical rotation in Xenopus eggs. Development, 130(22), 5425-5436. doi:10.1242/dev.00737

Pellegrino, T., Parak, W. J., Boudreau, R., Le gros, M. A., Gerion, D., Alivisatos, A. P., & Larabell, C. A. (2003). Quantum dot-based cell motility assay. Differentiation, 71(9), 542-548. doi:10.1111/j.1432-0436.2003.07109006.x

Parak, W. J., Gerion, D., Pellegrino, T., Zanchet, D., Micheel, C., Williams, S. C., Boudreau, R., Gros, M.A.L., Larabell, C.A., & Alivisatos, A. P. (2003). Biological applications of colloidal nanocrystals. Nanotechnology, 14(7), R15-R27. doi:10.1088/0957-4484/14/7/201


Parak, W. J., Boudreau, R., Le Gros, M., Gerion, D., Zanchet, D., Micheel, C. M., Williams, S.C., Alivisatos, A.P., & Larabell, C. (2002). Cell Motility and Metastatic Potential Studies Based on Quantum Dot Imaging of Phagokinetic Tracks. Advanced Materials, 14(12), 882-885. doi:10.1002/1521-4095(20020618)14:12<882::AID-ADMA882>3.0.CO;2-Y


Denbeaux, G., Anderson, E., Chao, W., Eimüller, T., Johnson, L., Köhler, M., Larabell, C.A., Le Gros, M.A., Fischer, P., Pearson, A., Schütz, G., Yager, D., & Attwood, D. (2001). Soft X-ray microscopy to 25nm with applications to biology and magnetic materials. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 467-468, doi:10.1016/s0168-9002(01)00480-6